A study on the effectiveness of a gel containing betamethasone 0.05 %, lidocaine 2%, and tetracaine 1% in reducing postoperative sore throat, hoarseness, cough, and coughing on the tube during emergence from anesthesia.

CRITICAL CARE & EMERGENGY MEDICINE VOL. 3

Estudio sobre la eficacia de un gel que contiene betametasona al 0,05 %, lidocaína al 2 % y tetracaína al 1 % para reducir el dolor de garganta, la ronquera, la tos y la tos en el tubo durante la salida de la anestesia.

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https://doi.org/10.58281/ccem241209051

Soto-Hopkins Sergio 1 , Milla Hector 2, Hernández Oros Karina3 , Gualajara Figueroa Cesar Jared 2.

1 Department of Anesthesiology, TJ Plast Advanced Center for Plastic Surgery, Tijuana.
2 Department of Surgery, TJ Plast Advanced Center for Plastic Surgery, Tijuana.
3 Department of Pharmacology, TJ Plast Advanced Center for Plastic Surgery, Tijuana.

Abstract

Postoperative sore throat is a common complaint and an undesirable outcome. It is often a side effect of general anesthesia, reported by 30% to 70% of patients following tracheal intubation.
Despite advancements in laryngoscopy equipment, postoperative sore throat remains a common issue, requiring additional pharmacological interventions and negatively affecting patient satisfaction. This highlights the continued need for effective strategies to tackle this challenge in clinical practice.
This study is a retrospective cohort analysis involving 101 patients who underwent elective plastic surgery with orotracheal intubation under general anesthesia. The research compares the incidence of postoperative sore throat, hoarseness, and cough, as well as coughing upon emergence from anesthesia, between two types of lubricated endotracheal tubes: one coated with a gel containing 0.05% betamethasone, 2% lidocaine, and 1% tetracaine, and another with 2% lidocaine jelly.
At the 8-hour mark after extubation, the incidence of postoperative sore throat was significantly lower in the experimental group at 17.6%, compared to 58% in the 2% lidocaine jelly group (P<0.001). Over the 24-hour evaluation, the experimental group consistently showed a lower incidence of postoperative sore throat at all measured time points.
The 2% lidocaine group had an OR 2.0 CI 95% (1.48-2.93), 2.28 CI 95% (1.54-3.3), and 2.4 CI 95% (1.64-3.5) for postoperative sore throat at post-anesthesia care unit, 8 hours and 24 hours after surgery evaluation respectively.
Our research highlights the potential benefits of applying a gel that contains corticosteroids and local anesthetics to the tracheal tube. This application may help reduce postoperative complications associated with tracheal intubation, including sore throat, coughing, irritation from the tube, and hoarseness.

El dolor de garganta posoperatorio es una queja común y un resultado indeseable. A menudo es un efecto secundario de la anestesia general, reportado por el 30% al 70% de los pacientes después de la intubación traqueal.
A pesar de los avances en el equipo de laringoscopia, el dolor de garganta posoperatorio sigue siendo un problema común, que requiere intervenciones farmacológicas adicionales y afecta negativamente la satisfacción del paciente. Esto resalta la necesidad continua de estrategias efectivas para abordar este desafío en la práctica clínica.
Este estudio es un análisis de cohorte retrospectivo que involucra a 101 pacientes que se sometieron a cirugía plástica electiva con intubación orotraqueal bajo anestesia general. La investigación compara la incidencia de dolor de garganta, ronquera y tos posoperatorias, así como tos al despertar de la anestesia, entre dos tipos de tubos endotraqueales lubricados: uno recubierto con un gel que contiene 0,05% de betametasona, 2% de lidocaína y 1% de tetracaína, y otro con gel de lidocaína al 2%. A las 8 horas posteriores a la extubación, la incidencia de dolor de garganta posoperatorio fue significativamente menor en el grupo experimental, con un 17,6 %, en comparación con el 58 % en el grupo tratado con gel de lidocaína al 2 % (P < 0,001). Durante la evaluación de 24 horas, el grupo experimental mostró de manera consistente una menor incidencia de dolor de garganta posoperatorio en todos los puntos de tiempo medidos.
El grupo tratado con lidocaína al 2 % tuvo un OR de 2,0 IC 95 % (1,48-2,93), 2,28 IC 95 % (1,54-3,3) y 2,4 IC 95 % (1,64-3,5) para el dolor de garganta posoperatorio en la unidad de cuidados postanestésicos, 8 horas y 24 horas después de la evaluación de la cirugía, respectivamente.
Nuestra investigación destaca los posibles beneficios de aplicar un gel que contiene corticosteroides y anestésicos locales al tubo traqueal. Esta aplicación puede ayudar a reducir las complicaciones posoperatorias asociadas con la intubación traqueal, incluido dolor de garganta, tos, irritación del tubo y ronquera.

Postoperative Sore Throat, General Anesthesia, Endotracheal Intubation, 2% Lidocaine Jelly, 0.05% Betamethasone, Coughing at Emersion.

Soto-Hopkins Sergio
Department of Anesthesiology, TJ Plast Advanced Center for Plastic Surgery, Tijuana.

Milla Hector
Department of Surgery, TJ Plast Advanced Center for Plastic Surgery, Tijuana.

Hernández Oros Karina
Department of Pharmacology, TJ Plast Advanced Center for Plastic Surgery, Tijuana. Gualajara

Figueroa Cesar Jared
Department of Surgery, TJ Plast Advanced Center for Plastic Surgery, Tijuana.

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[1] Soto-Hopkins Sergio, Milla Hector, Hernández Oros Karina, and Gualajara Figueroa Cesar Jared. 2024. A study on the effectiveness of a gel containing betamethasone 0.05 %, lidocaine 2%, and tetracaine 1% in reducing postoperative sore throat, hoarseness, cough, and coughing on the tube during emergence from anesthesia. CRITICAL CARE & EMERGENGY MEDICINE. Vol. 3, pp. 46–51. DOI: https://doi.org/10.58281/ccem241209051.

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2992-6785

eISSN: 2992-6785
DOI: 10.3989/ccem

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